Secondary and tertiary protein structure I. Hierarchy of protein structure
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چکیده
Four levels in protein structural organization are commonly identified. Primary structure is a sequence of amino acids. Secondary structure is represented by regular local conformations of polypeptide chain, such as α-helix or β-strand. The combinations of two secondary structure elements are also sometimes referred to as secondary (or supersecondary) structure. The example is a β-hairpin formed by two adjacent β−strands. The entire 3D distribution of protein atoms is termed as tertiary structure. Quaternary structure describes the 3D arrangement of individual domains in large multidomain proteins.
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